Care following diagnosis HCP leaflet : focused on the care after diagnosis
This guide provides healthcare professionals with essential information about Angelman syndrome, including its genetic causes, clinical characteristics, diagnosis and management. Developed by the Foundation for Angelman Syndrome Therapeutics (FAST), it offers practical guidance to support informed care and improve outcomes for individuals living with Angelman syndrome.
Diagnosis HCP leaflet: focused on diagnosing AS
This guide provides healthcare professionals with essential information on recognising and diagnosing Angelman syndrome, including common symptoms, genetic testing and the importance of early diagnosis. It also highlights ongoing research and the potential for future treatments.
Angelman Syndrome Leaflet (Ages 7-11)
A child-friendly information leaflet introducing Angelman syndrome, what it means and how it can affect everyday life. Designed to help schoolchildren understand differences, communicate with kindness and support classmates with Angelman syndrome, while highlighting the work of FAST UK.
School Talk – Let’s talk about Angelman Syndrome (ages 4-6)
A friendly, age-appropriate introduction to Angelman syndrome, designed for children aged 4–6. This school presentation helps young pupils understand that everyone is different, encouraging kindness, friendship and inclusion through simple, accessible explanations.
School Talk – What is a chromosome (Year 7-11)
Aimed at pupils in Years 7–11, this school presentation explains what chromosomes are, how they carry genetic information and the role they play in our bodies. It introduces key genetic concepts in a clear, age-appropriate way.
Science Booklet for Families
Our FAST Science Booklet for Families presents Angelman syndrome research in a simple, visual, and accessible way. This booklet helps families understand current studies, scientific approaches and what research means for the community. You can now explore the digital version as a flipbook.
When a clinical trial changes or ends
Clinical trials can sometimes change, pause or stop earlier than planned. Find out why this might happen, how families may hear updates, and where to turn for information and support.
Find Current Clinical Trials
Looking for information about Angelman syndrome clinical trials? FAST’s Clinical Trial Finder lets you explore studies using filters such as age, location and recruiting status.
Helpful Resources
Roadmap to a Cure – Family Guide to Angelman Syndrome
Our Roadmap to a Cure Family Guide includes a dedicated section, “From Benchside to Bedside: Understanding Clinical Trials,” which explains:
How treatments move from research into clinical trials
The different phases of clinical research
Why control groups and placebos are sometimes needed
What families can expect throughout the process
What Parents Need to Know About Ongoing and Upcoming Clinical Trials
As research into Angelman syndrome continues to move forward, many families are beginning to think about clinical trials and what taking part might mean for them.
We know this can feel exciting, but also a little overwhelming.
The aim of this page is to bring together trusted information that will help you better understand the clinical trial process, the language you may hear, and the questions you might want to ask. We hope these resources will help you feel informed and prepared, whatever stage of the journey you’re on.