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Help us Find a Cure for
Angelman Syndrome

Welcome to the Foundation for Angelman Syndrome Therapeutics UK.
We have one goal: to cure Angelman Syndrome.

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Newly Diagnosed?
Global Angelman Syndrome Registry

What is Angelman Syndrome?

Angelman syndrome is a rare genetic disorder that affects the nervous system, leading to severe developmental delays, speech impairments, and balance issues. Individuals with Angelman syndrome often exhibit a happy, excitable demeanour and enjoy social interactions, but they may also face challenges with movement, coordination, and learning. This condition, typically identified in early childhood, is caused by changes on chromosome 15 and requires lifelong care and support. As we work towards a brighter future for those affected, your support can make a meaningful difference.
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Drug Development Pipline

It’s our job to push forward all promising Angelman syndrome (AS) programs, and to ensure that the community has a birds-eye view of the entire landscape.

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Meet Bella...

Our journey pretty much started when Bella was born – she had a really tough birth, time in intensive care and the hospital was a second home really with many specialists and investigations which then led to genetic specialist involvement. The hospital is still a second home and we are really grateful for Bella’s team of healthcare specialists who make sure she’s getting the best help and every opportunity…
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Has your loved one been newly diagnosed with Angelman Syndrome?

If your loved one has recently been diagnosed with Angelman Syndrome, you’re not alone. It can feel overwhelming, confusing, and uncertain, but there is support available. On this page, you’ll find clear information about Angelman Syndrome, what it means, and what to expect. You can also reach out to our team directly for guidance, support, or simply someone to talk to.
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Need support or advice?

We’re here for you, just reach out.
Your information is kept private and will only be used to respond to your enquiry.

The Latest at FAST UK

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Alton Towers IAD Weekend 2026 – Celebrating 13 Years!

The 2026 Alton Towers event for International Angelman Day marked an incredible 13 years of bringing families together for a weekend of fun, connection, and celebration!

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Scientific Updates

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FAST Global

This website is operated by FAST UK, an independent entity organised and existing under the laws of (England and Wales).  While FAST UK uses the branding of the Foundation for Angelman Syndrome Therapeutics, FAST UK is a separate and distinct entity, operating under its own governance.

At FAST UK, we’re dedicated to keeping our community informed about advancements in Angelman syndrome treatments. We’ve provided a link to the global FAST site, where you can explore an up to date overview of the drug development pipeline. This resource highlights the progress of various programs, some of which are supported by FAST and others disclosed by external organisations.

Click below to gain insight into the promising developments bringing us closer to effective treatments and, ultimately, a cure.

FAST Global
Prof Art Beaudet

There are many disorders that will not be cured or treated in our lifetime, but Angelman Syndrome will not be one of them.