2024 Global Science Summit Recap
The 17th Global Science Summit brought together over 1,000 in-person and virtual attendees from 55 countries around the world!
Sleep in Angelman & Dup15q Syndromes
Explore the differences in sleep patterns between Angelman Syndrome and Dup15q. Understand the causes, treatment options, and future research directions for sleep issues in these syndromes.
Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse Brain
Explore how an artificial transcription factor can restore Ube3a expression in an Angelman Syndrome mouse brain. Discover the protein delivery process, tracking, and future challenges.
Ovid: Towards Improved Outcomes in Rare Neurodevelopmental Disorders Via Targeted Treatments
Discover OVID’s innovative approach to improving outcomes in rare neurodevelopmental disorders. Learn about our upcoming trial in Angelman Syndrome and our unique treatment, OV101.
Next Steps for Dup15q/Angelman Syndrome Research
Explore the challenges and future directions in Dup15q and Angelman Syndrome research. Discussing the role of HERC2, limitations of animal models, and the need for broader therapeutic targeting.
Levodopa in Angelman Syndrome: Results of a Multicenter Randomized Controlled Trial
Explore the results of a multicenter randomized controlled trial on the use of Levodopa in Angelman Syndrome. Discover the scientific basis, trial process, and key findings.
Hurdles to be Overcome for a Trial of Oligonucleotide Therapy in Angelman Syndrome
Explore the potential of oligonucleotide therapy in Angelman Syndrome, discussing challenges in mouse behaviour analysis, humanised mouse creation, and docking strategies. Discover the complexities of UBE3A regulation.
Gene Reviews Overview of Dup15q Syndrome, Angelman Syndrome & the Critical Region
Explore an in-depth overview of Dup15q and Angelman Syndrome, genetic disorders linked to chromosome 15, characterized by developmental delays, autism, epilepsy, and more.
Dendritic Spine Development in Dup15q and AS
Explore the intriguing study on dendritic spine development in Dup15q and AS, highlighting the role of UBE3A and actin dynamics. Discover how VirtualCell software aids in understanding this complex process.
Cannabidiol for Epilepsy
Explore the use of cannabidiol (CBD) for epilepsy treatment. Learn about its history, effectiveness, trial results, and potential side effects. Understand the need for more scientific studies on CBD.