LGIT and Ketogenic Diets for Angelman Syndrome

Quick Overview

This summary discusses the benefits of Low Glycemic Index Therapy (LGIT) and ketogenic diets for children with Angelman Syndrome. The speaker emphasises the importance of gradually transitioning to these diets, focusing on quality of life and enjoyment of food. The diets involve cutting out simple sugars, juices, soda, candy, processed sugars, and hidden carbohydrates, and transitioning to low glycemic index carbohydrates. Recommended foods include lean meats, dairy products, vegetables, and fruits with high fibre content. The speaker also highlights the benefits of MCT oil for constipation and the importance of drinking water. Potential side effects of these diets include dehydration, low blood sugar, metabolic acidosis, constipation, inflammation of the pancreas, kidney stones, growth and vitamin deficiencies, and increased cholesterol levels. The speaker concludes by emphasising the importance of monitoring these diets under the supervision of a physician and a dietitian.

Introduction

The focus of this talk is on the Low Glycemic Index Treatment (LGIT) and ketogenic diets for managing Angelman Syndrome. The emphasis is on gradually transitioning to these diets, as it has been observed that people are more likely to adhere to the diet if they are eased into it. The goal is not to be overly restrictive, but to improve the quality of life of the child.

Transitioning to Low Glycemic Index Carbohydrates

Children with Angelman Syndrome often derive a lot of enjoyment from eating. Therefore, the aim is to cut out simple sugars, juices, soda, candy, processed sugars, and hidden carbohydrates like barbecue sauce. The focus is on transitioning to low glycemic index carbohydrates, which is 40 to 60 grams of carbohydrates a day.

Recommended Foods

The recommended foods include protein foods like eggs, lean cuts of meat, and dairy products. However, caution should be exercised with dairy products as milk has a lot of carbohydrates. Almond milk is a possible alternative for children above the age of two. It is also important to ensure that they are getting plenty of dairy products for calcium intake.

Monitoring and Complications

It is crucial to monitor the child’s diet under the supervision of a physician and a dietitian. This is because there can be complications associated with the diet. For instance, a child who transitions from a standard American diet to a ketogenic diet may have problems with blood sugar.

Transitioning to Solids

Transitioning to solid foods is another important aspect of managing Angelman Syndrome. It is recommended to start with purees and monitor the child for any signs of discomfort. Avocado or pureed green beans are good options to introduce to the diet.

Side Effects and Management

Dehydration is a common side effect of the ketogenic diet. Therefore, it is important to ensure that the child is drinking plenty of water. Other side effects include low blood sugar, metabolic acidosis, constipation, and a risk of kidney stones.

Conclusion

In conclusion, the LGIT and ketogenic diets can be beneficial for managing Angelman Syndrome. However, it is important to transition to these diets gradually and under the supervision of a healthcare professional. The focus should always be on improving the child’s quality of life.

Talk details

  • Title: LGIT and Ketogenic Diets for Angelman Syndrome
  • Author(s): Jessica Duis
  • Author(s)’ affiliation: Vanderbilt University School of Medicine
  • Publication date: 2019-09-06
  • Collection: 2019 ASF Family Conference